Alkali treatment of renal osteodystrophy.

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Alkali treatment of renal osteodystrophy.

In 1960 a 5-year-old girl was found to have developed accelerated hypertension (B.P. 190/150) with blood urea 119 mg/ 100 ml. An intravenous pyelogram showed a small scarred left kidney (5-3 by 32 cm). There was also upper pole scarring with clubbed calyces on the right side. Left nephrectomy was performed and histological examination of the kidney confirmed pyelonephritic changes, and showed i...

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Pathogenesis and treatment of renal osteodystrophy.

Renal osteodystrophy is the term used to describe the many different patterns of the skeletal abnormalities that occur in patients with chronic kidney disease. The main two conditions are osteitis fibrosa, characterized by high bone turnover, increased osteoclastic and osteoblastic activity, and high levels of circulating parathyroid hormone (PTH) and adynamic bone disease characterized by low ...

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The incidence of chronic renal disease is increasing, and the pattern of renal osteodystrophy seems to be shifting from the classic hyperparathyroid presentation to one of low bone turnover. Patients with persistent disease also live longer than previously and are more physically active. Thus, patients may experience trauma as a direct result of increased physical activity in a setting of weake...

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Effects of treatment of renal osteodystrophy on bone histology.

Renal osteodystrophy is characterized by abnormalities in bone turnover, mineralization, and bone volume. The effects of treatment modalities for renal osteodystrophy on bone should be analyzed with respect to these abnormalities. The major treatment modalities for renal osteodystrophy include phosphate binders, vitamin D compounds, and calcimimetics. Aluminum-containing phosphate binders have ...

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201 - Renal osteodystrophy

2013 whose GFR is reduced due to intrinsic parenchymal damage as opposed to age-related reductions in GFR without another specific intrinsic renal diagnosis. At each level of CKD there may exist a specific form of renal osteodystrophy. The earliest form of renal bone disease (secondary hyperparathyroidism) may be defined by quantitative histomorphometry and/or biochemical profiling (elevated 1-...

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ژورنال

عنوان ژورنال: BMJ

سال: 1972

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.4.5839.529